Indoximod + Keytruda looks promising in Phase 2 advanced melanoma
IDO (indoleamine-2,3-dioxygenase) is an intracellular enzyme found in antigen presenting cells that mediates immune suppression in the tumor microenvironment. Continue reading
Category Archives: IDO
Immunotherapy of Cancer: Roche & NewLink $1 Billion Deal for IDO Inhibition
Roche (Genentech) entered into a $1 billion deal with NewLink Genetics, a company with an IDO (indoleamine 2,3-dioxygenase) inhibitor. Continue reading
IND for Clinical Studies of dCellVax Breast Cancer Immune Therapy Filed – Intelligent and Rational Gene Silencing Approach for Cancer
Regen Biopharma recently filed an IND (Investigational New Drug Application) with the FDA to permit the initiation of Phase 1 clinical trials of its dCellVax treatment for advanced breast cancer. Continue reading