Cancer Biology

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Tag Archives: RB

DNAtrix and Merck Phase II Collaboration of Oncolytic Virus + Keytruda for Glioblastoma

DNAtrix and Merck announced a collaboration to combine oncolytic virus therapy and PD-1 inhibition – the two companies will collaborate in phase II clinical trials on a therapy to treat glioblastoma, an especially deadly cancer for which there is no cure. Continue reading →

This entry was posted in active immunotherapy, Checkpoint Inhibitors, Mutations, Oncogenes, passive immunotherapy, Uncategorized and tagged checkpoint control, DNAtrix, DNX-2401, glioblastoma, integrin, Keytruda, Merck, oncolytic virus, PD-1, PD-L1, pembrlizumab, RB, RGD-4C on October 7, 2015 by Joseph Gulfo.

Why more males develop brain tumors than females

It is widely known that brain tumors, in particular glioblastomas and medulloblastomas, affect males more than females. Moreover, given the age of onset and analysis of incidence by age, sex hormones have been ruled-out as the cause. Continue reading →

This entry was posted in Cell Cycle, Signal Transduction, Tumor Suppressor Genes, Uncategorized and tagged CDK4/6, Cyclin D, Cyclin E, glioblastoma, Joshua Rubin, medulloblastoma, pRb, RB, retinoblastoma gene, Roberta Moldow, tumor suppressor genes on August 25, 2014 by Joseph Gulfo.

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This blog is designed to provide updates in developments in cancer biology and engage in discussions about new findings in the field.

Sponsored by the Department of Biology, Seton Hall University.

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