Cancer Biology

Discussions of New Developments and Updates

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Tag Archives: APC

Photo-immunotherapy approaches for cancer

The NCI (National Cancer Institute) highlighted two photo-immunotherapy (PIT) approaches that employ antibodies conjugated to phthalocyanine dye IRDye 700DX (IR700). Continue reading →

This entry was posted in active immunotherapy, Antibodies & Conjugates, Immunology & Immunotherapy, Oncogenes, passive immunotherapy, Uncategorized and tagged Antibody Photon Absorber Conjugate, APC, CD25+, EGFR, mesothelin, mesothelioma, photo-immunotherapy, phthalocyanine dye IRDye 700DX, PIT, regulatory T-cells, Treg on October 26, 2016 by Joseph Gulfo.

CD40 Antibody for Immunotherapy of Cancer Licensed by Janssen from Alligator

Janssen Biotech acquired a worldwide license to Alligator Bioscience’s Phase I immunotherapy ADC-1013, an agonistic monoclonal antibody that targets CD40, an immuno-stimulatory receptor found on antigen-presenting cells, which can spur an increase in T cells attacking a tumor. Continue reading →

This entry was posted in active immunotherapy, Antibodies & Conjugates, Immunology & Immunotherapy, Uncategorized and tagged ADC 1013, Alligator, APC, cancer, CD40, dendritic cells, immunomodulation, intratumoral therapy, J&J, Janssen on August 26, 2015 by Joseph Gulfo.

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This blog is designed to provide updates in developments in cancer biology and engage in discussions about new findings in the field.

Sponsored by the Department of Biology, Seton Hall University.

@josephgulfo

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