Tag Archives: phosphatidyl-serine

BXQ-350 – Pre-clinical Cancer Drug with Novel Mechanism of Action

Bexion Pharmaceuticals received Orphan Drug Designation for its novel drug, BXQ-350 for the treatment of patients with glioblastoma multiforme. The drug has shown activity in over 60 different cancer cell lines, and is toxic to cancer cells, only.The nanovesicals bypass the blood brain barrier. Continue reading

Bavituximab – Novel Checkpoint Inhibitor in Phase 3

Bavituximab is a monoclonal antibody that binds to phosphatidyl serine (PS), a molecule this is expressed in the inner side of the cell membrane. The drug is being developed by Peregrine Pharmaceuticals for the treatment of non-small cell lung cancer and is in a late stage trial called SUNRISE –  A Phase III, Randomized, Double-Blind, Placebo-Controlled Multicenter Trial of Bavituximab Plus Docetaxel Versus Docetaxel Alone in Patients With Previously Treated Stage IIIb/IV Non-Squamous Non Small-Cell Lung Cancer. Continue reading