Aduro Biotech just signed a $750MM ($200MM of which was up-front) deal with Novartis for the development of modulators of the STING pathway to enhance the immunogenicity of cancer cells. Continue reading
Tag Archives: innate immunity
Innate Pharma – Two NK Cell Checkpoint Inhibitors in Development
Natural Killer cells and macrophages are essential in the innate immune response to bacterial pathogens. They also provide the essential link to the adaptive immune response by presenting antigens to dendritic cells and by directly stimulating CD8+ cytotoxic T-cells.
