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Cancer Biology

Tag Archives: irAE

Early discontinuation of checkpoint inhibition due to immune-related side effects does not have a significant impact on treatment efficacy

A course of treatment with checkpoint inhibitors Yervoy (ipilimumab) and Opdivo (nivolumab) for patients with unresectable or metastatic melanoma is every 3 weeks for a total of four doses. Almost forty percent of patients receiving this combined regimen discontinue treatment because of  immune-related adverse events. Continue reading →

This entry was posted in active immunotherapy, Checkpoint Inhibitors, Immunology & Immunotherapy, Uncategorized and tagged checkpoint inhibitor, immune-related adverse events, ipilimumab, irAE, nivolumab, Opdivo, Yervoy on November 1, 2017 by Joseph Gulfo.


This blog is designed to provide updates in developments in cancer biology and engage in discussions about new findings in the field.

Sponsored by the Department of Biology, Seton Hall University.

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