Tag Archives: melanoma

Novel mutated antigens from Tumor Infiltrating Lymphocytes from long-term melanoma responders

Tumor Infiltrating Lymphocytes (TILs) are cytotoxic T-cells that are found in tumors.  They serve to destroy cancer, or at least keep cancer at bay.  Adoptive immunotherapy, Continue reading

Nivolumab Phase 3 study stopped early for efficacy

Great news – nivolumab, BMS’ PD-1 immune checkpoint control inhibitor was shown to prolong overall survival when used front-line in patients with advanced melanoma.  The study was stopped early, that is before it fully enrolled the planned number of patients, by an independent data monitoring committee because it was shown to be quite effective. Continue reading