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Cancer Biology

Tag Archives: O6-methylguanine

New data with temozolomide plus radiation for brain cancers

The results of two studies have demonstrated that the use of temozolomide (TMZ) plus radiation increases disease-free and overall survival in patients with glioblastoma and a low grade glioma called anaplastic glioma. Continue reading →

This entry was posted in Cell Cycle, Checkpoint Inhibitors, DNA Repair, Resistance, Stem Cells, Traditional Chemotherapy, Uncategorized and tagged base excision repair, BER, CTLA4, DNA repair, glioblastoma, homologous recombination, HR, ipilimumab, Lynparza, methylguanine methyltransferase, MGMT, mismatch-repair, NHEJ, nivolumab, non-homologous end joining, O6-methylguanine, olaparib, PD-1, Pembrolizumab, temozolomide, TMZ on August 3, 2016 by Joseph Gulfo.


This blog is designed to provide updates in developments in cancer biology and engage in discussions about new findings in the field.

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