The Ras onogene has been studied for 30 years, with over 40,000 scientific articles published on it.  However, an inhibitor of the mutated form of Ras has not been able to be developed.  So, researchers have developed downstream blockers of the Ras cascade – MEK inhibitors and Raf inhibitors, for example.  But why can’t a molecule that blocks mutated Ras be identified? Continue reading →