Cancer Biology

Discussions of New Developments and Updates

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Tag Archives: LGR

Targeting Cancer Stem Cells – OncoMed’s R-SPONDIN LGR Antibody for Colorectal Cancer

OncoMed initiated a Phase I/II trial of its anti-RSPO3 antibody (OMP-131R10) in patients with relapsed colorectal cancer. Patients will also be receiving FOLFIRI (5-FU, irinotecan, leucovorin). Continue reading →

This entry was posted in Apoptosis, Gene Regulation / Gene Control, Growth Receptors, Stem Cells, Traditional Chemotherapy, Uncategorized and tagged 5-FU, anti-RSP03, beta-catenin, colorectal cancer, irinotecan, LGR, OMP-131R10, R-spondin, stem cells, Wnt on August 12, 2015 by Joseph Gulfo.

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This blog is designed to provide updates in developments in cancer biology and engage in discussions about new findings in the field.

Sponsored by the Department of Biology, Seton Hall University.

@josephgulfo

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