Tag Archives: James P. McCauley

Combination Therapy of Immune Checkpoint Inhibitors to Combat Lung Cancer – James P. McCauley, Contributor

Researchers at AstraZeneca have completed a small-scale study which demonstrated the synergistic benefit of utilizing two immunotherapy drugs to combat non-small cell lung cancer (NSCLC) over just a single immunotherapy drug. The study found that utilizing an immune checkpoint inhibitor for PD-1, called durvalumab, in combination with another immune checkpoint inhibitor for CTLA-4, called tremelimumab, had a tumor response rate of 23% for metastatic NSCLC. Researchers at AstraZeneca are, indeed, confident that combination immune checkpoint therapy is the key to developing more efficient immunotherapies to target and effectively treat cancer. Continue reading