Cancer Biology

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Tag Archives: acute myeloid leukemia

Gilteritinib in Patients with Relapsed and Refractory Acute Myeloid Leukemia

Adult acute myeloid leukemia (AML) is a cancer of the blood and bone marrow. This type of cancer usually gets worse quickly if it is not treated. Continue reading →

This entry was posted in Apoptosis, Growth Receptors, Receptor Tyrosine Kinase Inhibitors, Signal Transduction and tagged acute myeloid leukemia, AML, AXL, FLT-3, FLT3, Gas6, Gilteritinib, Leukemia, PI3K on November 4, 2015 by Joseph Gulfo.

Merck Acquires OncoEthix for Novel MYC Blocker

Last week, Merck acquired OncoEthix at a price of $375 MM for OTX015, a synthetic small molecule which targets the BET bromodomain proteins 2, 3, and 4 (BRD2/3/4). Continue reading →

This entry was posted in Cell Cycle, Gene Regulation / Gene Control, Oncogenes, Signal Transduction, Transcription Factors and tagged acute myeloid leukemia, AML, BET bromodomain proteins, Burkitt's Lymphoma, Merck, myc, OncoEthics, OTX015, p15, p16, p21, p27, transcription factors on December 23, 2014 by Joseph Gulfo.

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This blog is designed to provide updates in developments in cancer biology and engage in discussions about new findings in the field.

Sponsored by the Department of Biology, Seton Hall University.

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