Limited Competition: Renewals of, and Revisions and Resubmissions to, the Longitudinal Early-onset Alzheimers Disease Study (LEADS) Cooperative Agreement (U01 Clinical Trial Not Allowed)
NIA invites revision, resubmission, and renewal applications to the Early Onset AD Consortium: Longitudinal Early-Onset Alzheimer’s Disease Study (LEADS), a longitudinal observational study of early onset dementia (EOD). LEADS was originally an application responding to PA-16-160 (NIH Research Project Grant – Parent R01), which NIA funded after conversion to a cooperative agreement (U01). LEADS studies subjects with early onset dementia, ages 40-65, using amyloid PET scans to separate out amyloid-positive subjects with EOD (presumably early onset Alzheimer’s disease, or EOAD) from amyloid-negative EOD subjects. Amyloid-positive EOAD subjects are followed annually for 2 years with multimodal neuroimaging and fluid biomarkers. NIA funded an administrative supplement to the first 2 years of LEADS to allow follow up beyond 2 years for all EOD subjects, additional biomarker characterization of amyloid-negative EOD subjects, and additional neuropathology capabilities.
Competitive revision applications could include, but are not limited to, continuation of activities initially funded by NIA’s administrative supplement (ongoing annual visits, biomarker characterization of amyloid-negative EOD subjects, and additional neuropathology) through the project end date.
Funding Agency: NIH
Deadline: July 5, 2022
For more information: https://grants.nih.gov/grants/guide/pa-files/PAR-19-338.html
Circadian Patterns of Gene Expression Associated with Disease (R01 – Clinical Trial Optional)
The purpose of this Funding Opportunity Announcement (FOA) is to identify abnormalities in circadian-ordered gene expression to improve our understanding of disease phenotypes, etiology, risk stratification, resilience, and therapeutic management in diseases.
Funding Agency: NIH
Deadline: November 7, 2019
Amount: $400,000
For more information: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-20-016.html
OSERS-OSEP: Technical Assistance on State Data Collection—National Technical Assistance Center to Improve State Capacity to Collect, Report, Analyze, and Use Accurate IDEA Part B Data
The mission of the Office of Special Education and Rehabilitative Services (OSERS) is to improve early childhood,educational, and employment outcomes and raise expectations for all people with disabilities, their families, their communities, and the Nation. As such, the Department of Education(Department) is issuing a notice inviting applications for new awards for fiscal year (FY) 2019 for a National Technical Assistance Center to Improve State Capacity to Collect, Report, Analyze, and Use Accurate IDEA Part B Data, Catalog of Federal Domestic Assistance (CFDA) number 84.373Y. This notice relates to the approved information collection under OMB control number 1894-0006.
Funding Agency: Department of Education
Deadline: September 11, 2019
Amount: $6,500,000
For more information: Go to grants.gov and search opportunity #ED-Grants-081219-002
Secondary Analyses of Strengthening Families Datasets
The Office of Planning, Research, and Evaluation (OPRE) within the Administration for Children and Families (ACF) in the Department of Health and Human Services (HHS) plans to award up to ten cooperative agreements to fund research to conduct secondary data analysis of archived data, specifically the Building Strong Families (BSF), Supporting Healthy Marriage (SHM), and Parents and Children Together (PACT) datasets. These datasets are from large-scale federal evaluation impact studies, which addressed questions related to healthy marriage and/or responsible fatherhood. Successful applicants will demonstrate a familiarity with the proposed data for their analysis and an adequate understanding of the variables, sampling, methodology, etc. used to construct the dataset necessary for completion of the work proposed in the application. Proposed research should address topics relevant to strengthening families to improve the lives of children and parents, as well as promote economic stability. Topics of interest include, but may not be limited to the following: mediators of healthy marriage, relationship education, and/or fatherhood programs; measurement issues related to healthy marriage, relationship education, and/or fatherhood programs with low-income families; or father involvement in low-income families.
Funding Agency: Administration for Children and Families – OPRE
Deadline: October 11, 2019
Amount: $75,000
For more information: https://ami.grantsolutions.gov/HHS-2020-ACF-OPRE-PR-1565
Leveraging Cognitive Neuroscience to Improve Assessment of Cancer Treatment-Related Cognitive Impairment (R21 Clinical Trial Optional)
This FOA encourages the integration of cognitive neuroscience approaches to improve traditional assessment of acute and chronic cognitive changes following cancer treatment for non-central nervous system malignancies.
Complaints of persistent cognitive deficits are common among the increasing population of cancer survivors, particularly those who have undergone adjuvant chemotherapy, hormone therapies, immunotherapies, and/or molecularly-targeted cancer treatments. Systemically-treated cancer patients experience cognitive impairment during treatment, upon completion of regimens, and often as part of long-term survivorship. However, the specific nature and underlying mechanisms causing the cognitive impairments are often unclear. By leveraging advances in cognitive neuroscience, fundamental knowledge about the specific underlying mechanisms responsible for cognitive impairment may be obtained.
This FOA utilizes the Exploratory/Developmental Grant (R21) mechanism, which supports investigation of novel scientific ideas or new model systems, tools, or technologies that have the potential for significant impact on biomedical or biobehavioral research. An R21 grant application need not have extensive background material or preliminary information.
This FOA has a companion FOA with a similar scientific scope, PAR-19-340, which utilizes the Research Project Grant (R01) mechanism.
Funding Agency: NIH
Deadline: June 8, 2022
Amount: $200,000
For more information: http://grants.nih.gov/grants/guide/pa-files/PAR-19-339.html
OSERS-OSEP: Technical Assistance on State Data Collection: National Technical Assistance Center to Improve State Capacity to Collect, Report, Analyze, and Use Accurate Early Childhood IDEA Data
The mission of the Office of Special Education and Rehabilitative Services (OSERS) is to improve early childhood, educational, and employment outcomes and raise expectations for all people with disabilities, their families, their communities, and the Nation. As such, the Department of Education (Department) is issuing a notice inviting applications for new awards for fiscal year (FY) 2019 for a National Technical Assistance Center to Improve State Capacity to Collect, Report,Analyze, and Use Accurate Early Childhood IDEA Data,Catalog of Federal Domestic Assistance (CFDA) number 84.373Z. This notice relates to the approved information collection under OMB control number 1894-0006.
Funding Agency: Department of Education
Deadline: September 11, 2019
Amount: $6,500,000
For more information: Go to grants.gov and search opportunity # ED-Grants-081219-001
Leveraging Cognitive Neuroscience to Improve Assessment of Cancer Treatment-Related Cognitive Impairment (R21 Clinical Trial Optional)
This FOA encourages the integration of cognitive neuroscience approaches to improve traditional assessment of acute and chronic cognitive changes following cancer treatment for non-central nervous system malignancies.
Complaints of persistent cognitive deficits are common among the increasing population of cancer survivors, particularly those who have undergone adjuvant chemotherapy, hormone therapies, immunotherapies, and/or molecularly-targeted cancer treatments. Systemically-treated cancer patients experience cognitive impairment during treatment, upon completion of regimens, and often as part of long-term survivorship. However, the specific nature and underlying mechanisms causing the cognitive impairments are often unclear. By leveraging advances in cognitive neuroscience, fundamental knowledge about the specific underlying mechanisms responsible for cognitive impairment may be obtained.
This FOA encourages applications for well-developed research projects using the NIH R01 grant mechanism. This FOA runs in parallel with an FOA of similar scientific scope, PAR-19-339 , which utilizes the Exploratory/Developmental Grant (R21) mechanism.
Funding Agency: NIH
Deadline: June 8, 2022
For more information: http://grants.nih.gov/grants/guide/pa-files/PAR-19-340.html
Notice of Intent: Using Ground Based LIDAR to Monitor Accretion Rates and Biomass in Coastal Wetlands
Notice of Intent to award a cooperative agreement to the Rochester Institute of Technology in support of the project entitled “Using Ground Based Lidar to Monitor Accretion Rate and Biomass in Coastal Wetlands”. The main objective of this project is to test a new approach to collecting field data in mangrove forest. Rochester Institute of Technology is a world leader in developing innovative measurement technologies that are required to produce the most accurate data products about land surface elevation change and vegetation structure in relation to sea level rise. The terrestrial LIDAR instrument to be used in the collaboration is the most cost-effective and most accurate instrument for the measurements. USGS has maintained a long-term collaborative relationship with RIT to benefit from their international-leading expertise in field instrumentation and measurements.
Funding Agency: Geological Survey
Deadline: August 26, 2019
Amount: $60,000
For more information: Go to grants.gov and search opportunity # USGS-FA-19-0355
FY 2019 EDA Disaster Supplemental
EDA announces general policies and application procedures for the Disaster Supplemental NOFO. Subject to the availability of funds, this investment assistance will help communities and regions devise and implement long-term economic recovery strategies through a variety of non-construction and construction projects, as appropriate, to address economic challenges in areas where a Presidential declaration of a major disaster was issued under the Robert T. Stafford Disaster Relief and Emergency Assistance Act (42 U.S.C. § 5121 et seq.) (Stafford Act) “as a result of Hurricanes Florence, Michael, and Lane, Typhoons Yutu and Mangkhut, and of wildfires, volcanic eruptions, earthquakes and other natural disasters occurring in calendar year 2018, and tornadoes and floods occurring in calendar year 2019…”. To be competitive, applications must clearly incorporate principles for enhancing the resilience (as defined under Section A.4, below) of the relevant community/region or demonstrate the integration of resilience principles into the investment project itself. Resilience is an essential component of any strategy for mitigating the potential for future disaster-related losses and adverse economic impacts for communities. Therefore, inclusion of resilience principles in the project is a necessary step to improve the capacity of the region to recover more quickly from future disaster events. Applicants must include a narrative attachment as a part of their application materials, describing in detail the nexus between their proposed project scope of work and disaster recovery and resilience efforts. The strength of the nexus to the disaster is drawn from the consequences of the relevant disaster(s) and the intended project outcomes that fulfill the community’s specific post-disaster needs.
Funding Agency: Economic Development Administration
Deadline: Continuing Basis
Amount: $587,000,000
For more information: Go to grants.gov and search opportunity # EDA-2019-DISASTER
Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Clinical Trials (UG3/UH3 Clinical Trial Required)
The National Institutes of Health (NIH) participating Institutes and Centers, in coordination with the U.S. Food and Drug Administration (FDA), seeks highly meritorious clinical trial applications proposing to explore and enable the development of safe and effective regenerative medicine (RM) interventions using adult stem cells. This Funding Opportunity Announcement (FOA), issued as part of the Regenerative Medicine Innovation Project (RMIP), represents one step in fulfilling a statutory provision set forth in the 21st Century Cures Act. Applications submitted in response to this bi-phasic, milestone-driven cooperative agreement FOA are expected to propose highly innovative projects with a focus on solutions to widely-recognized issues in the development of safe and effective RM therapies. Of particular interest are projects using RM products that have undergone appropriate product development and pre-clinical studies and have demonstrated readiness to advance into clinical trials. This FOA seeks Phase I and beyond clinical trial applications that present a strong scientific rationale for the proposed clinical trial and a comprehensive scientific and operational plan. Trials must be relevant to the research mission of one or more participating NIH Institutes and Centers and meet the NIH definition of a clinical trial (see NOT-OD-15-015). Applications are expected to include plans for project management, participant recruitment and retention, performance milestones, conduct of the trial, and dissemination of results. Before the time of award and if applicable, successful applicants must obtain an Investigational New Drug (IND) authorization or Investigational New Device Exemption (IDE) approval to administer the product to humans. Successful applicants proposing the use of adult stem cells as a clinical intervention will be asked to make available representative samples of the source stem cell and clinical-grade stem cell-derived product for in-depth and independent characterization through the RM Innovation Catalyst (see description in Section I).
Funding Agency: NIH
Deadline: October 18, 2019
Amount: $3,118,000
For more information: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-20-030.html
Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 – Independent Clinical Trial Not Allowed)
The purpose of the MOSAIC Postdoctoral Career Transition Award to Promote Diversity (K99/R00) program is to support a cohort of early career, independent investigators from diverse backgrounds conducting research in NIH mission areas. The long-term goal of this program is to enhance diversity in the basic biomedical sciences research workforce. The MOSAIC K99/R00 program is designed to facilitate a timely transition of outstanding postdoctoral researchers from diverse backgrounds (e.g., see NIHs Interest in Diversity) from their mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions at research-intensive institutions. The MOSAIC K99/R00 program will provide independent NIH research support during this transition to help awardees launch competitive, independent research careers. Additionally, MOSAIC K99/R00 scholars will be part of organized scientific cohorts that will be expected to participate in mentoring, networking, and professional development activities coordinated by MOSAIC Institutionally-Focused Research Education Award to Promote Diversity (UE5) grantees.
Funding Agency: NIH
Deadline: November 14, 2022
For more information: https://grants.nih.gov/grants/guide/pa-files/PAR-19-343.html
Young Pacific Leaders Conference 2019/2020
U.S. Embassy Port Moresby announces an open competition for organizations interested in submitting proposals to organize a comprehensive program designed to provide emerging Pacific leaders with the skills and knowledge they need to become leaders in the region’s economic and civil development. As a Pacific nation, the United States has long been committed to working with partners in the region to enruse continued regional security, as well as economic growth and development. this program for young leaders will create ties across the Pacific to ensure that we are better prepared to address challenges together in the future.
Funding Agency: U.S. Mission to New Zealand
Deadline: September 13, 2019
Amount: $250,000
For more information: Go to grants.gov and search opportunity # PAS-PORTMORESBY-2019-002
HAZMAT Training at DOE Nuclear Weapons Complex (UH4 Clinical Trial Not Allowed)
The purpose of the NIEHS/DOE Nuclear Worker Training Program is to support the development of model programs for the training and education of workers engaged in activities related to hazardous materials and waste generation, removal, containment, transportation and emergency response within the DOE nuclear weapons complex.
Funding Agency: NIH
Deadline: November 21, 2019
Amount: $700,000
For more information: https://grants.nih.gov/grants/guide/rfa-files/RFA-ES-19-004.html
Explainable Artificial Intelligence for Decoding and Modulating Neural Circuit Activity Linked to Behavior (R01 Clinical Trial Optional)
Explainable Artificial Intelligence (XAI) aims to provide strong predictive value along with mechanistic understanding by combining machine learning techniques with effective explanatory techniques. This Funding Opportunity Announcement (FOA) solicits applications in the area of XAI applied to neuroscientific questions of encoding, decoding, and modulation of neural circuits linked to behavior. This FOA encourages collaborations between computationally and experimentally-focused investigators. This FOA seeks machine learning algorithms able to mechanistically explain how experimental manipulations can improve cognitive, affective, or social processing in humans or animals. Proof-of-concept applications aimed at improving the current state of the technology that use XAI to provide unbiased, hierarchical explanations of causal relationships between complex neural and behavioral data are also responsive.
Funding Agency: NIH
Deadline: March 10, 2022
For more information: http://grants.nih.gov/grants/guide/pa-files/PAR-19-344.html
Research Education: Short Courses on Alzheimer’s Disease and Related Dementias for Behavioral and Social Science (R25 Clinical Trial Not Allowed)
The goal of this FOA is to support short courses geared to behavioral and social scientists who have existing expertise in aging research and can make research contributions in Alzheimers disease and Alzheimer’s disease-related dementias (AD/ADRD) with additional knowledge about the diseaseand related research resources. Fields of behavioral and social science research relevant for this FOA are health economics, labor economics, health services research, healthcare policy, public policy, demography, sociology, social epidemiology, psychology, and social neuroscience. Priority areas of focus include, but are not limited to, the following: dementia care; dementia caregiver research; cognitive and dementia epidemiology; behavioral and social pathways of AD/ADRD; role of social, contextual, environmental, and institutional factors in AD/ADRD; early psychological changes preceding AD/ADRD onset; prevention of AD/ADRD; disparities in AD/ADRD or dementia-related outcomes; and research resources and methods for studying the determinants and impact of AD/ADRD.
Funding Agency: NIH
Deadline: January 21, 2020
Amount: $150,000
For more information: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-20-031.html
NEA Sound Health Network, FY2020
The Cooperative Agreement resulting from this Program Solicitation can start no earlier than July 1, 2020, and may extend for up to 18 months. An organization may submit only one proposal under this program solicitation. Program Description The Sound Health program seeks to expand public understanding of the connections between music and wellness: how music is processed by the brain, how music can impact development and learning, and the therapeutic use of music for specific health conditions. Launched in 2016, Sound Health is a partnership between the National Institutes of Health (“NIH”) and the John F. Kennedy Center for the Performing Arts (“Kennedy Center”), in association with the National Endowment for the Arts (“Arts Endowment”) (individually known as “Partner” and collectively known as “the Partnership”).
Funding Agency: National Endowment for the Arts
Deadline: November 19, 2019
Amount: $300,000
For more information: https://www.arts.gov/program-solicitation-sound-health-network
Hazardous Materials Worker Health and Safety Training (U45 Clinical Trial Not Allowed)
NIEHS invites applications for cooperative agreements to support the development of model programs for the training and education of workers engaged in activities related to hazardous materials and waste generation, removal, containment, transportation and emergency response. This funding opportunity announcement aims to prevent work-related harm through safety and health training. The training programs will transmit skills and knowledge to workers in how best to protect themselves and their communities from exposure to hazardous materials encountered during hazardous waste operations, hazardous materials transportation, environmental restoration of contaminated facilities or chemical emergency response. A variety of sites, such as those involved with chemical waste cleanup and remedial action and transportation-related chemical emergency response, may pose severe health and safety concerns to workers and the surrounding communities. These sites contain many hazardous substances, sometimes unknown, and often a site is uncontrolled. A major goal of the Worker Training Program (WTP) is to support institutional competency-building for the development and delivery of model training and education programs.
Funding Agency: NIH
Deadline: November 21, 2019
Amount: $700,000
For more information: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-19-003.html
Strengthening Education Systems with Proven Innovations in Developing Contexts
The Global Partnership for Education (GPE) and IDRC invite proposals for KIX Global Grants from individual organizations or groups of organizations for multi-region, multi-country projects that aim to develop, test, and apply ways to scale innovations that address key education issues. Projects funded through this global call must be multi-regional, involving at least three GPE member countries in at least two regions.
The projects funded under these grants will:
- generate knowledge and evidence to support the adaptation of proven innovations to address key education priorities in GPE member countries; and
- mobilize research and knowledge to support the scaling of these proven innovations.
Projects must also focus on one or more of the following six thematic areas:
- teaching and learning;
- early childhood care and education;
- equity and inclusion;
- gender equality;
- data systems; and
- learning assessment systems.
Funding Agency: International Development Research Centre (IDRC)
Deadline: October 1, 2019
Amount: $2,000,000
For more information: https://www.idrc.ca/en/funding/call-proposals-strengthening-education-systems-proven-innovations-developing-contexts
Breast Surgery Fellowships
The mission of the Breast Cancer Alliance is to improve survival rates and quality of life for those impacted by breast cancer through better prevention, early detection, treatment and cure. To promote these goals, the Breast Cancer Alliance invests in breast surgery fellowships.
Funding Agency: Breast Cancer Alliance, Inc.
Deadline: December 10, 2019
Amount: $75,000
For more information: https://breastcanceralliance.org/how-to-apply
Crazy 8 Initiative
The Crazy 8 Initiative Award will fund research into innovative and rigorous approaches that directly address the most intractable issues in pediatric cancer research today. This award is designed to coalesce cross-disciplinary cores of scientists working collaboratively in order to accelerate the pace of discovering new cures. The budget for this award is between $1-5 million USD over four years, and funding is set to begin by July 2020.
The goal of this award is designed to coalesce cross-disciplinary cores of scientists working collaboratively in order to accelerate the pace of discovering new cures. Investigations may involve the exploration of a novel scientific hypothesis or the development of new model systems, tools or technologies that have the potential for significant impact on the field of childhood cancer. We expect successful applications to propose multidisciplinary teams with a clear plan for collaboration that would empower the study of big ideas that would not be easily addressable otherwise. Childhood cancer research applicants are encouraged to bring new, necessary expertise into the field.
Funding Agency: Alex’s Lemonade Stand
Deadline: October 1, 2019
Amount: $20,000,000
For more information: https://www.alexslemonade.org/grants/program-areas/accelerator-programs?utm_campaign=Grant%20Application%20Openings&utm_source=hs_email&utm_medium=email&utm_content=74802218&_hsenc=p2ANqtz-8qek1l0rbH4gWAJPYJuk_KsFjO1ZqW39ac6d2QwNBppx-dtRHhjsw1jwXWmqZ4fbTbVegI0kXUw6tSop0WqSolwO3MK-eBTR1TAgLrdD7Z_z788BI&_hsmi=74802218#program-1047
Michelson Grants
Found Animals offers Michelson Grants of up to $250,000 USD per year for up to three years of funding for research in pursuit of a single-dose, permanent, nonsurgical sterilization product or technology for use in male and female dogs and cats.
To qualify for a Michelson Grant, a proposed project must pursue a technology, mechanism, or pathway representing an innovative approach to nonsurgical sterilization. Investigators are encouraged to submit for “proof of concept” studies in cell culture or rodents (in certain cases), and/or in dogs and cats.
The program’s goal is to bring to market a low-cost, permanent, nonsurgical sterilant or sterilants that will have a maximum impact in addressing populations of animals driving shelter intake.
Proposed research is not required to generate results that meet all of the Michelson Prize criteria in order to be funded (see: http://www.michelsonprizeandgrants.org/michelson-prize/criteria) and SPIN program no. 16998; however, strong preference will be given to projects with the potential to produce a prize-winning product or technology, and approaches must represent a significant improvement over existing products. Applicants are encouraged to review the process for applying for the Michelson Prize prior to submitting a letter of intent for a Michelson Grant, in order that the data obtained may later support a Prize application. Grant recipients are eligible to make claims for the Michelson Prize in the event that their research generates a product or technology that meets all the criteria.
Funding Agency: Found Animals Foundation
Amount: $750,000
For more information: https://www.michelsonprizeandgrants.org/michelson-grants/apply/